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Croda International Plc 1 oleoyl 2 hydroxy sn glycero 3 phosphocholine
1 Oleoyl 2 Hydroxy Sn Glycero 3 Phosphocholine, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 96/100, based on 253 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/845875p/18%3A1+Lyso+PC/pmc13171883-18-0-4
Average 96 stars, based on 253 article reviews
1 oleoyl 2 hydroxy sn glycero 3 phosphocholine - by Bioz Stars, 2026-09
96/100 stars

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Related Articles

Cell Culture:

Article Title: Glutaminase inhibition ameliorates cancer-associated fibroblast lipid support of pancreatic cancer cell growth.
Article Snippet: Cell growth was measured at the specified time points using the CellTiter-Glo 2.0 assay (Promega). .. For clonogenic assays, PDAC cells (5×104 per well) were seeded in 12-well plates with CAF-conditioned medium, or treated with 20 μM LPC 18:1 (Avanti Polar Lipids, 845875P), 5 mM NAC (Merck, A9165), 5 mM Glutathione ethyl ester (Cayman, 14953), 200 μM α-Ketoglutaric acid sodium salt (Thermo Scientific, 439350050), and 200–400 nM SCD inhibitor (Cayman, CAY10566) cultured under the indicated conditions for 72 hours, and stained with crystal violet. ..

Article Title: Glutaminase inhibition ameliorates cancer-associated fibroblast lipid support of pancreatic cancer cell growth
Article Snippet: Cell growth was measured at the specified time points using the CellTiter-Glo 2.0 assay (Promega). .. For clonogenic assays, PDAC cells (5×10 4 per well) were seeded in 12-well plates with CAF-conditioned medium, or treated with 20 μM LPC 18:1 (Avanti Polar Lipids, 845875P), 5 mM NAC (Merck, A9165), 5 mM Glutathione ethyl ester (Cayman, 14953), 200 μM α-Ketoglutaric acid sodium salt (Thermo Scientific, 439350050), and 200–400 nM SCD inhibitor (Cayman, CAY10566) cultured under the indicated conditions for 72 hours, and stained with crystal violet. ..

Staining:

Article Title: Glutaminase inhibition ameliorates cancer-associated fibroblast lipid support of pancreatic cancer cell growth.
Article Snippet: Cell growth was measured at the specified time points using the CellTiter-Glo 2.0 assay (Promega). .. For clonogenic assays, PDAC cells (5×104 per well) were seeded in 12-well plates with CAF-conditioned medium, or treated with 20 μM LPC 18:1 (Avanti Polar Lipids, 845875P), 5 mM NAC (Merck, A9165), 5 mM Glutathione ethyl ester (Cayman, 14953), 200 μM α-Ketoglutaric acid sodium salt (Thermo Scientific, 439350050), and 200–400 nM SCD inhibitor (Cayman, CAY10566) cultured under the indicated conditions for 72 hours, and stained with crystal violet. ..

Article Title: Glutaminase inhibition ameliorates cancer-associated fibroblast lipid support of pancreatic cancer cell growth
Article Snippet: Cell growth was measured at the specified time points using the CellTiter-Glo 2.0 assay (Promega). .. For clonogenic assays, PDAC cells (5×10 4 per well) were seeded in 12-well plates with CAF-conditioned medium, or treated with 20 μM LPC 18:1 (Avanti Polar Lipids, 845875P), 5 mM NAC (Merck, A9165), 5 mM Glutathione ethyl ester (Cayman, 14953), 200 μM α-Ketoglutaric acid sodium salt (Thermo Scientific, 439350050), and 200–400 nM SCD inhibitor (Cayman, CAY10566) cultured under the indicated conditions for 72 hours, and stained with crystal violet. ..

Sonication:

Article Title: Targeting Autotaxin with imidazole- and Triazolyl-based inhibitors: Biological insights from in vitro and in vivo studies in pulmonary fibrosis.
Article Snippet: Autotaxin (ATX) is a key enzyme in producing lysophosphatidic acid (LPA), a lipid involved in fibrosis.. This study reports the synthesis and evaluation of novel ATX inhibitors containing zinc-binding imidazole or triazole motif with piperidine spacers.. Compound 27a exhibited strong ATX inhibition (IC50 = 57 nM) in human plasma and demonstrated efficacy in cellular and animal fibrosis models.

Article Title: Discovery of triazolyl azabicyclo[3.1.0]hexane derivative as an autotaxin inhibitors for the treatment of pulmonary fibrosis.
Article Snippet: Autotaxin (ATX), the enzyme responsible for generating lysophosphatidic acid (LPA), is a validated target for fibrosis and cancer immunotherapy.. Current ATX inhibitors face challenges related to insufficient efficacy or safety concerns, reflecting trade-offs between zinc engagement and selectivity.. Here, we report a rigid triazolylazabicyclo[3.1.0]hexanyl–oxadiazolyl-pyrimidine scaffold developed through structure-based design, designed to potentially enhance ATX selectivity by promoting defined binding geometry.

other:

Article Title: Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Human: PSC #2 New York University, New York, NY A gift from Dr. Alec Kimmelman Human: CAF Fox Chase Cancer Center, Phialdelphia, PA A gift from Dr. Edna Cukierman Human: Pancreatic Microvascular Endothelial Cells iXCells Cat#SKU: 10HU-071 Murine: KPC4662 University of Pennsylvania, Philadelphia, PA A gift from Dr. Robert Vonderheide Murine: PSC New York University, New York, NY A gift from Dr. Alec Kimmelman Experimental models: Organisms/strains C57BL/6J mice JAX Cat#000664 Oligonucleotides TaqMan primerset: XBP1t Life Technologies Cat#HS00231936_M1 TaqMan primerset: XBP1s Life Technologies Cat#HS03929085_G1 TaqMan primerset: DDIT3 Life Technologies Cat#Hs00358796_G1 TaqMan primerset: HSPA5 Life Technologies Cat#Hs00946084_G1 TaqMan primerset: MFSD2A Life Technologies Cat#Hs00293017_m1 TaqMan primerset: LPCAT1 Life Technologies Cat#Hs00227357_m1 TaqMan primerset: LPCAT2 Life Technologies Cat#Hs01044164_m1 TaqMan primerset: LPCAT3 Life Technologies Cat#Hs01553683_m1 TaqMan primerset: LPCAT4 Life Technologies Cat#Hs00405723_m1 TaqMan primerset: 18S Life Technologies Cat#HS03928985_G1 Recombinant DNA XBP1 shRNA #1 Horizon Discovery Cat#TRCN0000019804 XBP1 shRNA #2 Horizon Discovery Cat#TRCN0000019806 Fasn shRNA #1 Horizon Discovery Cat#TRCN0000075703 Fasn shRNA #2 Horizon Discovery Cat#TRCN0000075706 pCDH-CMV-mCherry University of Pennsylvania, Philadelphia, PA A gift from Dr. Karin Eisinger LPCAT1 siRNA Horizon Discovery Cat#L-010289-00-0005 LPCAT2 siRNA Horizon Discovery Cat#L-010285-01-0005 LPCAT3 siRNA Horizon Discovery Cat#L-010273-01-0005 LPCAT4 siRNA Horizon Discovery Cat#L-016375-01-0005 MFSD2A siRNA Horizon Discovery Cat#L-014999-02-0005 Non-Targeting siRNA Control Horizon Discovery Cat#D-001206-13-20 Software and algorithms GraphPad PRISM 9.0.0 GraphPad N/A ImageJ 2.1.0/1.53c Open-source processing software N/A FlowJo 10.6.2 Software FlowJo LLC N/A Other Leica Microscope Leica Biosystems Cat#DM5000B BD FACS Calibur BD Biosciences N/A ViiA7 Real-Time PCR system Applied Biosystems N/A Countess Automated Cell Counter Invitrogen Cat#C10281 Amicon Ultra-15 Centrifugal Filter Unit Millipore Sigma Cat#UFC9003

Article Title: Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment
Article Snippet: LPC(18:1) , Avanti Polar Lipids , Cat845875P, CAS 9008-30-4.



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